The simplest no limit holdem tip for big pairs is to always give opponents incorrect odds. The best aspect of nl holdem is that you can control bet size at any time. Among other uses, it is great for giving opponents incorrect odds when trying to outdraw or outflop you.
To do this with big pairs you should make a bet preflop approximately 15% or more of the chips you will be risking during the hand. This will always give an opponent incorrect odds to try and outflop you with a smaller pair or any other hand.
What if everyone folds? It is better to win a small pot than lose a big one. Knowing when AA or KK become second best hand is not easy. And folding them is even harder. The best way to counter this is to use the odds/percentages before this happens. This tactic will show a profit in the long run as long as free cards are not given post flop.
The reasoning behind this strategy is the chance of an opponent flopping a set with a small pair is 11% (7.5 to 1). If you make it 15% or preferably more they will be getting improper odds for this type of hand, or for making two pair on the flop with a hand like QJ. The more opponents that enter the hand the bigger the preflop bet should be.
In any senario the best move if possible is all in preflop. Besides giving opponents the worst possible odds, this play is also best since if you are against a player with QQ or JJ and an Ace or King hits they will slow down or may even fold. This is also true if your opponent holds a hand like AK or AQ that can miss the flop.
The only downfall to getting it all in with KK is the unlikely event that someone has Aces. There is almost no way to get away from two Kings. However it is possible to do this with QQ and JJ, the big pairs that are most often misplayed. The No Limit Holdem Tip Section for QQ and JJ covers this and the right amount to raise pre-flop for them.
If you want to get tricky with AA or KK here is a no limit holdem tip for limping in or slow playing pre-flop.
If your the biggest stack, 15% of the chips being risked would mean, 15% of the biggest opponents stack. If your stack is the smaller of the two it would be 15% of your stack.